The present invention relates to a method for the treatment and / or prevention of SIRS and / or sepsis comprising the administration of an effective amount of a specific DPP-4 inhibitor, and a metabolic disease in a patient having or at risk of having SIRS and / or sepsis The use of specific DPP-4 inhibitors for the treatment and / or prevention of [Selection figure] None本発明は、有効量の特定DPP-4阻害薬の投与を含んでなるSIRS及び/又は敗血症の治療及び/又は予防方法、並びにSIRS及び/又は敗血症を有するか又はそのリスクがある患者の代謝疾患の治療及び/又は予防のための特定DPP-4阻害薬の使用に関する。【選択図】なし