Device for closing an opening (A) in a vascular wall (W), the opening having an external opening in an external region of the vascular wall and an internal opening in an internal region of the vascular wall, the device comprising: a member ( 40, 140) of covering which has a longitudinal and positionable axis inside the vessel against the internal opening of the opening, the covering member presenting a dimension to prevent the flow of fluid through the opening; a first spherical retainer (20) externally positionable with respect to the vessel; and a first suture (30, 150), the first spherical retainer (20) being attached to the first suture (30, 150), the first suture being further attached to the covering member such that when the suture is pulled proximally causes the first retainer to move towards the covering member (40, 140), characterized in that a second spherical retainer (22) is attached to a second suture (32, 152), the second suture being further attached to the covering member in such a way that when the suture (32, 152) is pulled proximally, the second retainer is advanced towards the covering member (40, 140).Dispositivo para cerrar una apertura (A) en una pared vascular (W), presentando la apertura una abertura externa en una región externa de la pared vascular y una abertura interna en una región interna de la pared vascular, comprendiendo el dispositivo: un miembro (40, 140) de cubrición que tiene un eje longitudinal y posicionable en el interior del vaso contra la abertura interna de la apertura, presentando el miembro de cubrición una dimensión para evitar la salida de fluido a través de la apertura; un primer retenedor esférico (20) posicionable externamente con respecto al vaso; y una primera sutura (30, 150), estando unido el primer retenedor esférico (20) a la primera sutura (30, 150), estando unida además la primera sutura al miembro de cubrición de tal modo que al tirar de la sutura proximalmente se hace mover el primer retenedor hacia el mi