KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK INC.
发明人:
JUNG, HEE JUNG,HA, JAE DU,CHO, SUNG YUN,KIM, HYOUNG RAE,LEE, KWANG HO,LEE, CHONG OCK,CHOI, SANG UN,PARK, CHI HOON
申请号:
CA2923533
公开号:
CA2923533C
申请日:
2013.09.30
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to a noveltriazolopyrazine derivative or a pharmaceuticallyacceptable salt thereof, and a pharmaceuticalcomposition containing the same as an active ingredientfor preventing or treating hyper proliferative disorder.The present invention can be useful as a therapeuticagent for various hyper proliferative disordersassociated with excessive cell proliferation and growthcaused by abnormal kinase activity, such as cancer,psoriasis, rheumatoid arthritis, and diabeticretinopathy, by efficiently inhibiting c-Met tyrosinekinase activity.