The invention relates to an arthralgia clearing traditional Chinese medicine composition used for treating arthralgia in a direct-current iontophoresis mode. The arthralgia clearing traditional Chinese medicine composition is prepared from angelica sinensis, achyranthes bidentata, red peony roots, angelica pubescens, caulis sargentodoxae, ginger, olibanum, myrrh, radix aconiti preparata, monkshood, pinellia ternate, eucommia ulmoides, fructus psoraleae and cistanche salsa. The invention further provides a preparation method of the arthralgia clearing traditional Chinese medicine composition and a direct-current iontophoresis system.