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compound, pharmaceutical composition, use of a compound, and methods for enhancing sleep quality, for treating insomnia and for treating or controlling obesity
专利权人:
MERCK SHARP & DOHME CORP.
发明人:
Jason W. Skudlarek,Scott D. Kuduk
申请号：
BR112014009486
公开号：
BR112014009486A2
申请日:
2012.10.17
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
1/1 summary "Compound, pharmaceutical composition, use of a compound, and methods for enhancing sleep quality, for treating insomnia and for treating or controlling obesity" The present invention It is directed to 2-pyridyloxy-4-nitrile compounds which are orexin receptor antagonists. The present invention is also directed to the uses of the 2-pyridyloxyoxy-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which they are present. orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to the use of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.1/1 resumo “composto, composiã‡ãƒo farmacãšutica, uso de um composto, e, mã‰todos para intensificar a qualidade do sono, para tratamento de insã”nia e para tratamento ou controle da obesidadeâ€� a presente invenã§ã£o ã© dirigida aos compostos 2-piridilã³xi-4- nitrila que sã£o antagonistas dos receptores de orexina. a presente invenã§ã£o tambã©m ã© dirigida aos usos dos compostos 2-piridil-ã³xi-4-nitrila descritos aqui no tratamento ou prevenã§ã£o de distãºrbios e doenã§as neurolã³gicas e psiquiã¡tricas em que os receptores de orexina estã£o envolvidos. a presente invenã§ã£o tambã©m ã© dirigida ã s composiã§ãµes farmacãªuticas compreendendo estes compostos. a presente invenã§ã£o ã© tambã©m dirigida ao uso destas composiã§ãµes farmacãªuticas na prevenã§ã£o ou tratamento de tais doenã§as em que os receptores de orexina estã£o envolvidos.
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
