XIE, ZIJIAN,SODHI, KOMAL,ABRAHAM, NADER,MARTIN, REBECCA,SHAPIRO, JOSEPH
申请号：
CA3064800
公开号：
CA3064800A1
申请日:
2018.05.25
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Expression vectors are provided that comprise a nucleic acid sequence encoding a polypeptide antagonist of a Na/K ATPase/Src receptor complex. The nucleic acid encoding the polypeptide antagonist is operatively linked to a promoter for expressing the polypeptide antagonist in a specific cell or tissue. Viral particles, target cells, and pharmaceutical compositions are also provided and include the expression vectors. Methods of treating a Src-associated disease is further provided and includes adminstering the expression vectors encoding the polypeptide antagonist of the Na/K ATPase/Src receptor complex to a subject in need thereof.
