THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;THE JOHNS HOPKINS UNIVERSITY;VANDERBILT UNIVERSITY
发明人:
WEISSMAN, DREW,SHAW, GEORGE M.,BAILEY, JUSTIN R.,RAY, STUART C.,CROWE, JAMES, JR.,FLYAK, ANDREW
申请号:
CA3061326
公开号:
CA3061326A1
申请日:
2018.04.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to compositions and methods for inducing an adaptive immune response against Hepatitis C virus (HCV) in a subject. In some embodiments, the present invention provides a composition comprising a nucleoside- modified nucleic acid molecule encoding a HCV antigen, adjuvant, or a combination thereof. For example, in some embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a HCV antigen, adjuvant, or a combination thereof.