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GAP JUNCTION INTERCELLULAR COMMUNICATION MODULATORS AND THEIR USE FOR THE TREATMENT OF DIABETIC EYE DISEASE
专利权人:
ZEALAND PHARMA A/S;BOSTON MEDICAL CENTER CORPORATION
发明人:
Bjarne Due LARSEN,Ulrik MOURITZEN,Dongjoon KIM,Sayon ROY
申请号:
US16609963
公开号:
US20200054602A1
申请日:
2018.05.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The use of gap junction intercellular communication (GJIC) modulators in the treatment or prevention of diabetic eye disease is disclosed, and more particularly to their use for the treatment or prevention of early stage diabetic retinopathy and diabetic macular edema by inhibiting apoptosis of retinal endothelial cells and inhibiting pericyte loss.
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