A manipulator system including a manipulator having a flexible manipulator provided with an elongated flexible insertion portion, a movable portion provided at a distal end of insertion portion, a driving portion provided at a proximal end of insertion portion and drives movable portion an operation input portion operated by operator and with which an operation instruction for flexible manipulator is input a control unit that controls driving portion based on operation instruction input via operation input portion an information input portion with which treatment-site specifying information for specifying a treatment target by using flexible manipulator is input and an information storage portion that sets a control parameter for controlling driving portion based on treatment-site specifying information, control unit controls driving portion based on the treatment-site specifying information input via information input portion using control parameter set by information storage portion.