Identification, Optimization and Use of Cryptic HLA-A24 Epitopes for Immunotherapy

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专利权人:

Kostantinos(Kostas) Kosmatopoulos

发明人:

Kostantinos(Kostas) Kosmatopoulos,Jeanne Menez-Jamet

申请号：

US13258227

公开号：

US20120082692A1

申请日:

2009.04.02

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention pertains to methods for identifying a HLA-A*2402-restricted cryptic epitope in an antigen, and for increasing its immunogenicity, in order to obtain HLA-A*2402-restricted epitopes able to trigger an immune response against HLA-A*2402-restricted cryptic epitopes. Isolated peptides consisting of cryptic or optimized HLA-A*2402-restricted epitopes are provided.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/