The divisional application of the invention relates to a human antibody preparation for targeted treatment of TNF ￣ α related diseases, which is mainly a liquid aqueous drug preparation.The liquid aqueous drug preparation can enhance the stability of anti TNF ￣ α antagonist antibody drugs such as recombinant human anti TNF ￣ α monoclonal antibody, and prolong its storage period in the aqueous preparation.The preparation of the invention is still stable after being stored at 40 ℃ for 4 weeks and light 4000lx test for 15 days, at least 5 cycles of freeze-thaw, 1 month at room temperature, and at least 36 months at 2-8 ℃.The preparation of the invention can be used for subcutaneous injection.本發明分案申請涉及一種靶向治療TNF‑α相關疾病的人抗體製劑，主要爲液體含水藥物製劑。所述液體含水藥物製劑可增強含重組人抗TNF‑α單克隆抗體等TNF‑α拮抗劑抗體藥物的穩定性，延長其在含水製劑中的保存周期。本發明的製劑在經過高溫40℃保存4周及光照4000lx試驗15天，至少5次循環凍融，室溫放置1個月後，2～8℃保存至少36個月，仍然保持穩定。本發明的製劑可用於皮下注射使用。
