Forming Iron Nitrosyl Hemoglobin

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专利权人:

Montana State University-Bozeman;Duke University

发明人:

Stamler, Jonathan S.,Singel, David J.

申请号：

AU2010201151

公开号：

AU2010201151B2

申请日:

2010.03.23

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2010201151B220121213.pdf#####ABSTRACT Contrary to current opinion that nitrite in general oxidizes hemoglobin with elimination of active nitric oxide, de-oxygenated hemoglobin reacts with low concentration inorganic nitrite to produce very stable iron nitrosyl hemoglobin which on delivery into the body is converted to a hemoglobin capable of nitric oxide delivery and provides vasodilator and antiplatelet activity. This provides basis for ameliorated risk blood product transfusions.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/