An air purification system includes a housing having an inlet and a panel. The panel at least partially defines a volume for receiving air from the inlet. The system also includes an internal support structure coupled to the housing and configured to support a plurality of components of the air purifier. The system further includes a blower configured to drive air through the air purifier components. The system also includes a first drawer including a mesh screen having a photocatalytic oxidation catalyst disposed on its surface. The first mesh screen is placed within the flow of air. The system further includes a second drawer including an ultraviolet light bulb in line-of-site position relative to the mesh screen. The system also includes a light shield configured to eliminate line-of-site access to the ultraviolet light bulb from an outlet of the air purification system.