Barton HAYNES B,Garnett KELSOE G,Israel LOWY I,Aris I. BARAS AI,Lynn MACDONALD L,John MCWHIRTER J,Cagan GURER C,Karolina A. MEAGHER KA,Andrew J. MURPHY AJ,George D. YANCOPOULOS GD,‧海恩斯,‧凱爾索,‧洛威,‧巴拉斯,‧麥克唐納,‧麥克維爾特,‧古雷爾,‧米蓋爾,‧莫菲
申请号：
HK16106896.4
公开号：
HK1218866A
申请日:
2016.06.15
申请国别(地区):
HK
年份:
2017
代理人:
摘要：
Non-human animals with humanized immunoglobulin loci and methods of using them in vaccine design are described, as well as methods for making broadly neutralizing antibodies against infectious agents and pathogens are provided. Non-human animals with humanized immunoglobulin loci used in B-cell-lineage immunogen design in vaccine development are provided, as are methods of carrying out such design.
