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Thieno-pyridine derivatives as MEK inhibitors
专利权人:
Judi Charlotte Neuss;Daniel Christopher Brookings;James Andrew Johnson;Martin Clive Hutchings;Barry John Langham
发明人:
James Andrew Johnson,Daniel Christopher Brookings,Martin Clive Hutchings,Barry John Langham,Judi Charlotte Neuss
申请号:
US12691842
公开号:
US08350037B2
申请日:
2010.01.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A series of thieno[2,3-b]pyridine derivatives which are substituted in the 2-position by a substituted anilino moiety, being selective inhibitors of human MEK (MAPKK) enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, proliferative (including oncological) and nociceptive conditions.
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