KOGA YUJI,MAENO KYOICHI,SATO IPPEI,IMAMURA YOSHIMASA,HANAZAWA TAKESHI,IIDA MAIKO,OHNE KAZUHIKO,IMAMURA KENICHIRO,WATANABE TSUBASA,NOZAWA EISUKE,SHIBATA HIROSHI,IMAMURA KE
申请号：
PL12791965
公开号：
PL2716642T3
申请日:
2012.05.29
申请国别(地区):
PL
年份:
2017
代理人:
摘要：
[Problem] An excellent drug for treating or preventing cardiovascular diseases, based on cGMP production enhancing action due to soluble guanylate cyclase activating action, is provided. [Means for Solution] It was found that imidazopyridine compounds having a carbamoyl group at the 3-position and a substituent bonded at the 8-position via an oxygen atom in an imidazo[1,2-a]pyridine skeleton exhibits a cGMP production enhancing action by a potent soluble guanylate cyclase activating action, and is useful as a drug for treating or preventing various soluble guanylate cyclase-related cardiovascular diseases, thereby completing the present invention.
