BAUDOUX GUY JEAN MARIE FERNAND PIERRE,RUELLE JEAN LOUIS,CYR SONYA L,RHEAULT PATRICK,BLAIS NORMAND
申请号:
NZ62057410
公开号:
NZ620574A
申请日:
2010.06.24
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
A recombinant respiratory syncytial virus (RSV) antigen comprising an RSV F protein polypeptide without a transmembrane domain, comprising an F2 domain and an F1 domain of an RSV F protein polypeptide, wherein the F protein polypeptide comprises at least one modification that increases glycosylation, which at least one modification that increases glycosylation comprises a substitution wherein amino acids corresponding to positions 500-502 of SEQ ID NO:2 are selected from: NGS NGT.