PROBLEM TO BE SOLVED: To provide an involucrin expression inhibitor which inhibits expression of involucrin, to provide a wavy hair-improving agent, and to provide a hair-softening agent.SOLUTION: The invention relates to an involucrin expression inhibitor containing Andrographis paniculata or extract thereof as an active ingredient.COPYRIGHT: (C)2016,JPO&INPIT【課題】インボルクリンの発現を抑制するインボルクリン発現抑制剤、くせ毛改善剤、及び軟毛化剤の提供。【解決手段】センシンレン又はその抽出物を有効成分とするインボルクリン発現抑制剤。【選択図】なし