The present invention relates to an ultrasound coupling device that includes a gel component and a coupling compartment. The present invention also relates to various kits and methods for using the ultrasound coupling device with low intensity ultrasound transducers and therapy. The present invention also relates to methods of making the ultrasound coupling device of the present invention. The present invention further relates to an array that includes a plurality of ultrasound coupling devices of the present invention and methods of using the array.
