An intelligent extension medicine box system, including a main control box and more than one sub-medicine box is provided. A main controller is arranged in the main control box, wherein a main connector is arranged on one side of the main control box. The sub-medicine box is formed by a box body and a box cover, wherein the inner part of the box body is divided into a medicine storage chamber and a sub-control chamber from top to bottom. A medicine bin with an inverted semi-conical bottom is arranged in the medicine storage chamber, wherein a medicine box light-emitting device and a detection device are arranged on the bottom of the medicine bin. A left connector and a right connector are arranged at the two sides of the sub-control chamber, wherein the left connector can be connected to the main control box or the right connectors of other sub-medicine boxes through the main connector.
