Disclosed is a method, a system, and a user interface for determining a preferred relative arrangement of digital restoration designs and digital representations of multi-shaded milling blocks for use when manufacturing dental restorations from multi-shaded milling blocks. A preferred first relative arrangement of a first digital restoration design and a digital representation of a first multi-shaded milling block is determined, and therefrom a preferred second relative arrangement of a second digital restoration design and a digital representation of a second multi-shaded milling block is determined.