Provided herein are biomarkers and therapies for the treatment of autoimmune and/or inflammatory diseases, such as lupus, and methods of using BTK inhibitors. In particular, provided are biomarkers for patient selection and prognosis in lupus, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.本發明提供用於治療諸如狼瘡之自體免疫及/或發炎疾病的生物標記物及療法，及使用BTK抑制劑之方法。特定言之，提供用於選擇狼瘡患者及預後之生物標記物以及醫療性治療之方法、製品及其製造方法、診斷套組、偵測方法及與其相關之推廣方法。
