BARTEL, STEPHAN,HAHN, MICHAEL,MORADI, WAHED, AHMED,MUENTER, KLAUS,ROELLE, THOMAS,STASCH, JOHANNES-PETER,SCHLEMMER, KARL-HEINZ,WUNDER, FRANK
申请号:
EP06806107.6
公开号:
EP1940811B1
申请日:
2006.10.09
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The invention relates to biphenyl compounds of formula (I): wherein U, V and W together form a group of the formula *&mdash;CH&boxH;CH&mdash;CH<;, *&mdash;CH2&mdash;CH2&mdash;CH<; or *&mdash;CH2&mdash;CH2&mdash;N<;, in which * means the point of linkage to the phenyl ring; A is O or CH2; and D, E, X, Y, Z, R1, R2, o, n, and p are as defined in the specification. The invention also relates to pharmaceutical compositions of the compound of the compounds. The compounds and pharmaceutical compositions of the invention can be used in the treatment or prevention of cardiovascular disorders.