An assembly and syringe adapter is provided. In one embodiment, an assembly includes a syringe and a syringe adapter. The syringe has a fluid reservoir and a tip that is in communication with the fluid reservoir. Additionally, the adapter has first and second ends, the first end including a cavity configured to receive the syringe tip, and a mating mechanism to permanently engage the syringe tip when the syringe tip is received in the cavity and the adapter is rotated in a first direction relative to the syringe. The adapter may not alter a volume of the syringe to maintain accuracy of volume indicia on the syringe.