W.H. Irwin McLean,Vikas Hedge,Deena M. Leslie Pedrioli,Sitheswaran Nainamalai,Paul A. Campbell,Frances J.D. Smith
申请号:
US14654325
公开号:
US20150342164A1
申请日:
2013.12.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is based upon the generation of a nucleic acid construct which may be used to generate transgenic non-human animals. The construct exploits a filaggrin based promoter region which directs the expression of a reporter sequence operatively linked thereto. The present invention provides a nucleic acid, said nucleic acid encoding a filaggrin promoter element and a nucleic acid sequence operatively linked thereto.