Fernando Jose Rebelo Do Couto;Kristin Beth Hendricks;Stacey Ellen Wallace
发明人:
Fernando Jose Rebelo Do Couto,Kristin Beth Hendricks,Stacey Ellen Wallace
申请号：
US13491239
公开号：
US08444984B2
申请日:
2012.06.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention provides monoclonal antibodies that neutralize TNFα activity. The monoclonal antibodies may be rabbit monoclonal antibodies or monoclonal antibodies having CDR regions derived from those rabbit monoclonal antibodies. In certain embodiments, the monoclonal antibodies may be humanized. Methods of using the subject antibodies to inhibit TNFα activity, methods of treatment using those antibodies and kits containing the same are also provided. The invention finds use in a variety of research and medical applications.
