The problem of the present invention is to provide acomposition for enhancing transdermal absorption of a drug,which shows a sufficiently high enhancing effect ontransdermal absorption of a drug, particularly, a compositionfor enhancing transdermal absorption of a drug, which shows asufficiently high enhancing effect on transdermal absorptionof an acidic drug.A composition for enhancing transdermal absorption of adrug, comprising an unsaturated higher alcohol having 12 - 20carbon atoms and a polyvalent alcohol having 3 - 8 carbonatoms. A composition for enhancing transdermal absorption of adrug, comprising an unsaturated higher alcohol having 12 - 20carbon atoms, a polyvalent alcohol having 3 - 8 carbon atomsand an organic amine having 2 - 9 carbon atoms.