crystalline forms of a janus kinase inhibitor

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专利权人:

JAPAN TOBACCO; INC.

发明人:

NORIAKI SHIMOYAMA,RYUHEI OKURA,SATORU NOJI,YUKIHIRO KAMIYA

申请号：

BR112019012210

公开号：

BR112019012210A2

申请日:

2017.12.20

申请国别(地区):

BR

年份:

2019

代理人:

摘要：

The present invention relates to crystalline forms of the janus kinase (jak) 3 - ((3s, 4r) -3-methyl-6- (7h-pyrrol [2,3-d] pyrimidin-4-yl) inhibitor ) -1,6-diazaspiro [3,4] octan-1-yl) -3-oxopropanenitrile (compound a), as well as their compositions, methods of preparation, methods of use, and methods of quantification.a presente invenção refere-se a formas cristalinas do inibidor de janus cinase (jak) 3-((3s,4r)-3-metil-6-(7h-pirrol[2,3-d] pirimi-din-4-il)-1,6-diazaspiro[3,4] octan-1-il)-3-oxopropanonitrila (composto a), assim como, suas composições, métodos de sua preparação, métodos de seu uso, e métodos de quantificação.

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