BASTIAN Jolie Anne,CHEN Jiehao,COHEN Jeffrey Daniel,HENRY James Robert,MCMILLEN William Thomas,REAMAN Bradley Earl,RUBIO Almudena,SALL Daniel Jon,ZHAO Gaiying
申请号：
MDE20190462
公开号：
MD3468965T2
申请日:
2017.05.31
申请国别(地区):
MD
年份:
2020
代理人:
摘要：
This invention refers to certain new 2,3-dihydro-1H-indole compounds, to pharmaceutical compositions containing compounds, and to methods of using compounds for the treatment of cancer, in particular for the treatment of selected cancer in the melanom a group, acute myeloid leukaemia,chronic lymphocytic leukaemia,colorectal cancer, breast cancer, lung cancer, ovarian cancer, uterine cancer, primary peritoneal cancer, cervical cancer, gastric cancer, liver cancer, pancreatic cancer, thyroid cancer, glioma, non-Hodgkin lymphoma, and Hodgkin lymphoma.Prezenta invenţie se referă la anumiţi compuşi 2,3-dihidro-1H-indol noi, la compoziţii farmaceutice care cuprind compuşii, şi la metode de utilizare a compuşilor pentru tratamentul cancerului, mai special pentru tratamentul cancerului selectat din grupul care constă din melanom, leucemie mieloidă acută, leucemie limfocită cronică, cancer colorectal, cancer la sȃni, cancer pulmonar, cancer ovarian, carcinom al trompei uterine, carcinom peritoneal primar, cancer cervical, cancer gastric, cancer la ficat, cancer pancreatic, cancer tiroidian, gliom, limfom non-Hodgkin, şi limfom Hodgkin.
