Apparatus for directed cranial access to a site includes a guidepiece and a receptacle. The receptacle includes lower and upper parts. The guidepiece includes a body having a bore defining an alignment axis. The guidepiece is dimensioned to fit rotatably within the receptacle. The bore is dimensioned to accept an imaging device, and an adaptor is provided, dimensioned to accept a device to be placed at the site. The imaging device is inserted into the bore and the guidepiece is swiveled until the image shows that the axis is aligned along an optimal trajectory to the site, the guidepiece is locked, and the imaging device is withdrawn. Then the adaptor is inserted into the bore, and the device is inserted through the adaptor along the established trajectory to the site. After placement of the device, the adaptor, guidepiece, and receptacle are removed while the device is held in place.