HARTMANN, TOBIAS,GRIMM, MARCUS OTTO WALTER,FLOSS, THOMAS,WITTMANN, ANKE
申请号：
CA2991086
公开号：
CA2991086A1
申请日:
2016.06.10
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention relates to an application of omega-3 and/or omega-6 fatty acid(s) for the therapeutic treatment of the human or animal body in the case of an impaired sphingolipid metabolism, in particular in the case of impaired sphingolipid synthesis and/or excessive sphingolipid degradation. In an embodiment of the invention, the agent is applied in the case of missing, reduced and/or defective formation of a sphingomyelin synthase enzyme in the body, in particular the enzyme sphingomyelin synthase 1 or the enzyme sphingomyelin synthase 2. The application has proved to be useful in the case of a defect of the sphingomyelin synthase 1 gene or of the sphingomyelin synthase 2 gene. The omega-3 and/or omega-6 fatty acid(s) preferably comprise(s) polyunsaturated omega-3 and/or omega-6 fatty acid(s), preferably EPA, DHA, DPA, ETA, 21:5n3 and/or SDA. The invention further relates to a method for determining a cause of a disease in an animal or a human being and to a device for carrying out the method.
