Winiany 5,8,14-triazatetracyklo [10.3.1.0<;sup>;2,11<;/sup>;.0<;sup>;4,9<;/sup>;]-heksadeka-2 (11),3,5,7,9-pentaenu, zawierajacy je srodek farmaceutyczny oraz zastosowanie tych zwiazków
BOGLE DAVID EVERETT,DAVID EVERETT BOGLE,ROSE PETER ROBERT,PETER ROBERT ROSE,WILLIAMS GLENN ROBERT,GLENN ROBERT WILLIAMS
申请号:
PL366551
公开号:
PL214876B1
申请日:
2002.04.26
申请国别(地区):
PL
年份:
2013
代理人:
摘要:
The present invention is directed to the tartrate salts of 5,8,14-triazatetracyclo[10.3.1.0<;SUP>;2,11<;/SUP>;.0<;SUP>;4,9<;/SUP>;]-hexadeca-2(11),3,5,7,9-pentaene: and pharmaceutical compositions thereof. The present invention in particular is directed to the L-tartrate salt, and further to the various polymorphs of the L-tartrate salt, including two distinct anhydrous polymorphs (referred to herein as Forms A and B) and a hydrate polymorph (referred to herein as Form C). In addition, the present invention is also directed to the D-tartrate salt of 5,8,14-triazatetracyclo[10.3.1.0<;SUP>;2,11<;/SUP>;.0<;SUP>;4,9<;/SUP>;]-hexadeca-2(11),3,5,7,9-pentaene and the various polymorphs thereof; as well as the D,L-tartrate salt thereof and its polymorphs, and the meso-tartrate salt thereof and its polymorphs.