Krzysztof Matyjaszewski,Ke Min,Jung Kwon Oh,James Spanswick,Nicolay V. Tsarevsky
申请号:
US12311673
公开号:
US08367051B2
申请日:
2007.10.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Functional gel particle formed from a crosslinked polymeric network including a fraction of stable crosslinks and a second fraction of cleavable crosslinks are disclosed. Functional compounds may be chemically or physically encapsulated within and/or released from the gel particle by selective cleavage of the cleavable crosslinks. The functional compounds may be delivered and released to a pre-selected target site. Peripheral or other accessible functionality on the surface of the gel particle allows attachment of a surface reactive agent, thereby modifying one or more surface properties of the gel particle. Processes of preparing the gel particles and processes of delivering the functional compounds to a target site are also disclosed.