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ゲル強度に優れた温度及びpH敏感性ブロック共重合体及びその製造方法、並びにそれを用いた薬物伝達体
专利权人:
成均館大学校産学協力団
发明人:
李 斗成,カサラ ダヤナンダ,金 奉燮
申请号:
JP2008096832
公开号:
JP5257885B2
申请日:
2008.04.03
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
Disclosed herein is a temperature- and pH-sensitive block copolymer having excellent gel strength, including: (a) a poly(ethylene glycol)-based compound (A) or a copolymer (B) of the poly(ethylene glycol)-based compound (A) and a biodegradable polymer and (b) a polyurethane-based oligomer (C). Further, a method of preparing a temperature and pH-sensitive block copolymer having excellent gel strength, including: (a) synthesizing a poly(ethylene glycol)-based compound (A) or a copolymer (B) of the poly(ethylene glycol)-based compound (A) and a biodegradable polymer and (b) coupling a polyurethane-based oligomer (C) with the copolymer (B), is disclosed. Also disclosed is a polymer hydrogel type drug delivery system, including: (a) the block copolymer and (b) a physiologically active substance which can be included in the block copolymer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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