Susan Mary Cramp,Hazel Joan Dyke,Thomas David Pallin,Robert Zahler
申请号:
US14878428
公开号:
US09561230B2
申请日:
2015.10.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides tricyclic sulfonamide compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tricyclic compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2. For example, the invention relates in part to tricyclic sulfonamide compounds represented by Formula I:or pharmaceutically acceptable salts or stereoisomers thereof, wherein A, B, D, RA1, RA2, Y, X and n are as defined herein.