KOHJIN LIFE SCIENCES CO., LTD.;THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
发明人:
Maurizio DEL POETA,Visesato MOR,Toshiya SATO,Tomohiro NAKAGAWA
申请号:
US15515318
公开号:
US20170224790A1
申请日:
2015.09.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention features compositions that include a fungal glucosylceramide (GlcCer) purified from a non-pathogenic fungus (e.g., Candida utilis) and, optionally, an adjuvant. The invention also features methods of treating a patient who has a fungal disease and methods of preventing a fungal disease in a subject by administration of these compositions. Also within the scope of the invention are methods of formulating a fungal vaccine by: (a) providing a fungal glucosylceramide isolated from a non-pathogenic fungus; and (b) combining the fungal glucosylceramide with an adjuvant in a physiologically acceptable excipient.