A sphingosine-1-phosphate 2 (S1P2) receptor antagonist of the formula: ** Formula ** wherein R1 is -CH3, R2 is -CH2CO2H or -CH2CH2OH, and R3 is 2,6-dichloropyridine substituted in 4, 2-Chloro-6-hydroxyethylpyridine substituted in 4,2-chloro-6-hydroxypropyl-pyridine substituted in 4, 2- (aminoethyl) -6-chloro-pyridine substituted in 4, 2- (aminoethylmethyl) -6-chloro-pyridine substituted in 4, 2,3-dichloro-thiophene substituted in 5 and its physiologically acceptable salts and solvates.Un antagonista del receptor de esfingosina-1-fosfato 2 (S1P2) de fórmula:**Fórmula** en la que R1 es -CH3, R2 es -CH2CO2H o -CH2CH2OH, y R3 es 2,6-dicloropiridina sustituida en 4, 2-cloro-6-hidroxietilpiridina sustituida en 4, 2-cloro-6-hidroxipropil-piridina sustituida en 4, 2-(aminoetil)-6-cloro-piridina sustituida en 4, 2- (aminoetilmetil)-6-cloro-piridina sustituida en 4, 2,3-dicloro-tiofeno sustituido en 5 y sus sales y solvatos fisiológicamente aceptables.
