CHEUNG, NAI-KONG V.,LOPEZ-ALBAITERO, ANDRES,XU, HONG
申请号:
CA2956014
公开号:
CA2956014A1
申请日:
2015.07.24
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Provided herein are compositions, methods, and uses involving bispecific binding molecules that specifically bind to HER2, a receptor tyrosine kinase, and to CD3, a T cell receptor, and mediate T cell cytotoxicity for managing and treating disorders, such as cancer. Also provided herein are uses and methods for managing and treating HER2 -related cancers.