Melissa Fleury;Roland Gendron;Jane Schmidt;Adam D. Hughes
发明人:
Melissa Fleury,Roland Gendron,Adam D. Hughes,Jane Schmidt
申请号：
US13475076
公开号：
US09499487B2
申请日:
2012.05.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
In one aspect, the invention relates to compounds having the formula:where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds； methods of using such compounds； and process and intermediates for preparing such compounds.
