PROBLEM TO BE SOLVED: To provide a method and composition for diagnosing and treating diseases associated with amyloidosis.SOLUTION: There are provided molecular constructs including expression vectors encoding fusion proteins comprising: at least one segment comprising a binding region which binds to an epitope or fragment and at least one segment comprising portions, fragments or whole proteins that are capable of crossing the blood brain barrier.COPYRIGHT: (C)2012,JPO&INPIT【課題】アミロイド関連疾患の診断及び治療のための方法及び組成物。【解決手段】エピトープ又は断片に結合する結合領域を含む少なくとも一つのセグメント、及び血液脳関門を横切ることのできる部分、断片又は全タンパク質を含む少なくとも一つのセグメントを含む融合タンパク質をコードする発現ベクターを含む分子構築物。【選択図】なし
