Dino Di Carlo,Westbrook Weaver,Tatiana Segura,Jaekyung Koh,Philip Scumpia,Donald R. Griffin
申请号:
US16077985
公开号:
US20200306413A1
申请日:
2017.02.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A hydrogel material for modulating an immune response in a human subject or other mammal includes a collection of microgel particles having one or more network cross linker components, wherein the microgel particles, when exposed to an endogenous or exogenous annealing agent, links the microgel particles together in situ to form a covalently-stabilized scaffold of microgel particles having interstitial spaces formed between the microgel particles and wherein the collection of microgel particles further includes at least one of an antigen and an adjuvant.