KROPP JASON,LANE BENJAMIN S.,ISBESTER PAUL,MARTIN MICHAEL,REN PINGDA
申请号：
ARP120100083
公开号：
AR084824A1
申请日:
2012.01.10
申请国别(地区):
AR
年份:
2013
代理人:
摘要：
This report introduces the various forms of chemical compounds used to regulate the activity of Quinza, including the activity of PI3 Quinza, as well as the compounds, pharmaceutical components and disease treatment methods related to the activity of Quinza, including the activity of PI3 Quinza. In addition, in this procedure, they also specify the compound, its multi form, its pharmaceutical composition and the same required AMOLIN form 5: the multi form C of a formula compound (1). Requirement 6: according to requirement 5, variable,where the polymorph has the following characteristic X-ray powder diffraction (XRPD) peaks: 2q = 10.4º (± 0.2º),133 (02)and 24.3º (± 0.2º). Claim 10: The Form B polymorph of a compound of formula (1). Claim 11: The polymorph according to claim 10, wherein the polymorph has the following characteristic XRPD peaks: 2q = 7.9 ° (± 0.2 °),134 (02)and 23.4º (± 0.2º). Claim 15: The Form D polymorph of a compound of formula (1). Claim 16: The polymorph according to claim 15, wherein the polymorph has the following characteristic XRPD peaks: 2q = 11.4 ° (± 0.2 °),174 (02)and 22.9º (± 0.2º). Claim 20: The Form E polymorph of a compound of formula (1). Claim 21: The polymorph according to claim 20, wherein the polymorph has the following characteristic XRPD peaks: 2q = 6.7 ° (± 0.2 °),93 (02)and 24.4º (± 0.2º). Claim 25: The Form F polymorph of a compound of formula (1). Claim 26: The polymorph according to claim 25, wherein the polymorph has the following characteristic XRPD peaks: 2q = 9.6 ° (± 0.2 °),173 (02)and 24.6º (± 0.2º). Claim 30: The Form G polymorph of a compound of formula (1). Claim 31: The polymorph according to claim 30, wherein the polymorph has the following characteristic XRPD peaks: 2q = 6.7 ° (± 0.2 °),95 (02)and 19.0º (± 0.2º). Claim 35: The Form H polymorph of a compound of formula (1). Claim 36: The polymorph according to claim 35, wherein the polymorph has the following characteristic XRPD peaks: 2q = 8.9 ° (± 0.2 °),92 (
