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1,4-disubstituted naphthalenes as inhibitors of p38 map kinase
专利权人:
Jason Hill;Mark A. Ashwell;Yanbin Liu;Syed M. Ali;Woj Wrona
发明人:
Mark A. Ashwell,Yanbin Liu,Syed M. Ali,Jason Hill,Woj Wrona
申请号:
US12854687
公开号:
US08114873B2
申请日:
2010.08.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Naphthalene-based compounds having linked heterocyclic and aromatic rings capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating conditions associated with P38 activity or cytokine activity; more particularly naphthalene-based compounds of Formula (I) having a morpholine heterocyclic ring, and methods of use thereof
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