GOLDMAN, Erick,SMYTH, Mark Stephen,BONNAUD, Thierry,SULEIMAN, Osama,WORRALL, Christopher Peter
申请号：
EP16773865
公开号：
EP3273962A4
申请日:
2016.03.25
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Disclosed are co-crystals of the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the co-crystals, as well as methods of using co-crystals, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
