ASKLEPIOS BIOPHARMACEUTICAL, INC.;UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
发明人:
SAMULSKI, R. JUDE,AGBANDJE-MCKENNA, MAVIS,BENNETT, ANTONETTE
申请号:
CA3095127
公开号:
CA3095127A1
申请日:
2019.03.28
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
As demonstrated herein, a modified recombinant AAV6 vector is provided that transduces the liver and has reduced neutralization of transduction of liver by ADK6 antibody. Accordingly, embodiments of the invention relate to liver tropic rAAV6 vectors that evade neutralization.