PYRROLINE DERIVATIVES AGAINST CELL RELEASING TUMOR NECROSIS FACTOR, PREPARATION METHODS AND USES THEREOF

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专利权人:

发明人:

申请号：

EP07816579.2

公开号：

EP2083011B1

申请日:

2007.10.16

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

Compounds represented by Formula (I) or Formula (II) against cell releasing TNFα, their pharmaceutically acceptable salts or hydrates and preparation methods and uses thereof, in which A and B represent CH2, CO, SO, or SO2 D represents S, NH, or NC1-6 alkyl R1 represents H, or one or two same or different radical(s) selected from the group consisting of F, Cl, Br, C1-4 alkyl,OH,OC1-4 alkyl,NO2,NHC(O)C1-4 alkyl,NH2,NH(C1-4 alkyl), or N(C1-4 alkyl)2.

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中国工程科技知识中心

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http://www.ckcest.cn/home/