Dina Schneider,Rimas J. Orentas,Boro Dropulic,Peirong Hu
申请号:
US16584308
公开号:
US20200087396A1
申请日:
2019.09.26
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Chimeric antigen receptors containing CD19/CD22 or CD22/CD19 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.