The Compound pirazolil - 1 - 3 - (4 - ((2 - anilinopirimidin - 4-yl) oxy) naftalen - 1 - il) urea or its Salts, inhibitor of p38 Mitogen Activated Protein Kinases; Crystalline Solid Pharmaceutical composition; Combination; Pharmaceutical; and their use in asthma, cystic fibrosis, allergic rhinitis psoriasis, entr And other
KING-UNDERWOOD, JOHN,ITO, KAZUHIRO,CHARRON, CATHERINE ELISABETH,ONIONS, STUART THOMAS,LONGSHAW, ALISTAIR IAN,BROECKX, RUDY,FILLIERS, WALTER,COPMANS, ALEX
申请号:
CL2014000813
公开号:
CL2014000813A1
申请日:
2014.04.02
申请国别(地区):
CL
年份:
2014
代理人:
摘要:
There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and COPD.COMPUESTO 1-(3-TER-BUTIL-1-P-TOLIL-1H-PIRAZOL-5-IL)-3-(4-(2-(FENILAMINO)PIRIMIDIN-4-ILOXI)NAFTALEN-1-IL)UREA, INHIBIDOR DE CINASAS DE LA PROTEINA ACTIVADA POR EL MITOGENO P38; COMPOSICION FARMACEUTICA; COMBINACION FARMACEUTICA; Y USO EN EL TRATAMIENTO DE ASMA, FIBROSIS QUISTICA, SARCOIDOSIS, RINITIS Y PSORIASIS, ENTRE OTROS.