シアル酸誘導体の製造方法とインフルエンザウィルス阻害剤としての利用
- 专利权人:
- 国立大学法人埼玉大学
- 发明人:
- 鈴木 香織,坂本 純一,松岡 浩司,照沼 大陽,幡野 健,鈴木 康夫
- 申请号:
- JP2008150046
- 公开号:
- JP5327839B2
- 申请日:
- 2008.06.09
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要:
To provide a compound effectively inhibiting intrusion of an influenza virus (especially type A virus) into a cell and/or release of the virus from an infected cell.
SOLUTION: Provided are a sialic acid derivative compound expressed by general formula (i) (in the formula, R
1 is a 2-12C alkyl group and alkenyl group containing a double bond or alkynyl group containing a triple bond wherein all groups may contain 1-2 amide bonds R2 is a carboxy group, a hydroxy group or a 1-15C alkyl group and alkenyl group or alkynyl group bonded through a sulfide group and R3 is a case exchanged with R2 and is a hydroxy group, or a 1-15C alkyl group, alkenyl group and alkynyl group or a carboxy group bonded through a sulfide group), its pharmacologically permissible salt or hydrate and an antiviral agent containing the compound or its pharmacologically permissible salt or hydrate as an active component.COPYRIGHT: (C)2010 and JPO& INPIT
- 来源网站:
- 中国工程科技知识中心