The present invention relates to a cardiopulmonary resuscitation device that measures electrocardiogram and oxygen saturation during a cardiopulmonary resuscitation procedure, detects brain activity in real time which is a degree of blood circulation to the brain by measuring electroencephalogram, is equipped with a defibrillation function, uses a brain activation index as a CPR signal indicating a degree of cardiopulmonary resuscitation, and is capable of bio signal remote monitoring in a pre-hospital step. The cardiopulmonary resuscitation device includes an electroencephalogram detection unit for detecting an electroencephalogram signal in the frontal lobe and a calculation processing unit for detecting a brain activation index from an electroencephalogram signal received by the electroencephalogram detection unit. The cardiopulmonary resuscitation device uses a brain activation index as a CPR signal indicating a degree of cardiopulmonary resuscitation, and the brain activation index is any one of a burst suppression ratio (BSR), a beta ratio, and a relative synchrony of fast and slow wave (SynchFastSlow, SFS). The calculation processing unit removes a noise in an electroencephalogram signal received by the electroencephalogram detection unit and calculates a beta ratio from the electroencephalogram signal in which a noise has been removed according to: Beta Ratio = log spectral power 30 ˆ’ 47 Hz / spectral power 11-20Hz (where spectral power (30-47Hz) is a power spectrum of 30 to 47Hz in the electroencephalogram and spectral power (11-20Hz) is 11 to 20Hz in the electroencephalogram).
